Article
A mathematical description of nonself for biallelic genetic systems in pregnancy, transfusion, and transplantation.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Nov 2024
Rieneck Klaus
Abstract excerpt
A central issue in immunology is the immunological response against nonself. The prerequisite for a specific immunological response is the exposure to the immune system of a nonself antigen. Mathematical equations are presented, which define the fraction of all outcomes with a nonself allele in biallelic systems at the population level in pregnancy and transfusion/transplantation medicine. When designing assays,...
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