Article
Integration of Genetic and Clinical Risk Factors for Risk Classification of Uveitis in Patients With Juvenile Idiopathic Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Dec 2024
Tordoff Melissa, Smith Samantha L, Lawson-Tovey Saskia, Dick Andrew D, Beresford Michael W, Ramanan Athimalaipet V, Hyrich Kimme L, Morris Andrew P, Eyre Stephen, Wedderburn Lucy R, Bowes John
Abstract excerpt
OBJECTIVE: Juvenile idiopathic arthritis (JIA)-associated uveitis (JIAU) is a serious JIA comorbidity that can result in vision impairment. This study aimed to identify genetic risk factors within the major histocompatibility complex for JIAU and evaluate their contribution for improving risk classification when combined with clinical risk factors. METHODS: Data on single nucleotide polymorphisms, amino acids,...
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