Article
HLA Associations in a Cohort of Children With Juvenile Idiopathic Arthritis With and Without Uveitis.
Investigative ophthalmology & visual science - 1 Sept 2015
Angeles-Han Sheila T, McCracken Courtney, Yeh Steven, Jang Se Ryeong, Jenkins Kirsten, Cope Spencer, Bohnsack John, Hersh Aimee, Thompson Susan D, Prahalad Sampath
Abstract excerpt
PURPOSE: Juvenile idiopathic arthritis (JIA)-associated uveitis can lead to ocular complications and vision loss. Alleles HLA-DRB1*08, *11, and *13 are risk alleles for JIA, whereas HLA-DRB1*11 and *13 alleles increase uveitis susceptibility. We examined the association of common HLA-DRB1 alleles in children with JIA alone and JIA-associated uveitis. METHODS: High-resolution HLA-DRB1 genotyping was performed in...
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