Article
Investigation of gyrA and parC mutations and the prevalence of plasmid-mediated quinolone resistance genes in Klebsiella pneumoniae clinical isolates.
BMC microbiology - 18 Jul 2024
Rezaei Sepideh, Tajbakhsh Saeed, Naeimi Behrouz, Yousefi Forough
Abstract excerpt
BACKGROUND: The emergence of fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae is a growing concern. To investigate the mechanisms behind this resistance, we studied a total of 215 K. pneumoniae isolates from hospitals in Bushehr province, Iran, collected between 2017 and 2019. Antimicrobial susceptibility test for fluoroquinolones was determined. The presence of plasmid mediated quinolone...
Topics
- Klebsiella pneumoniae
- DNA Gyrase
- Plasmids
- DNA Topoisomerase IV
- Humans
- Anti-Bacterial Agents
- Klebsiella Infections
- Microbial Sensitivity Tests
- Drug Resistance, Bacterial
- Mutation