Article
Determination of gyrA and parC mutations and prevalence of plasmid-mediated quinolone resistance genes in Escherichia coli and Klebsiella pneumoniae isolated from patients with urinary tract infection in Iran.
Journal of global antimicrobial resistance - 1 Jun 2018
Mirzaii Mehdi, Jamshidi Sanaz, Zamanzadeh Maryam, Marashifard Masoud, Malek Hosseini Seyed Ali Asghar, Haeili Mehri, Jahanbin Fariba, Mansouri Fariba, Darban-Sarokhalil Davood, Khoramrooz Seyed Sajjad
Abstract excerpt
OBJECTIVES: Fluoroquinolones (FQs) are recommended as the drugs of choice for the empirical treatment of urinary tract infections (UTIs). This study investigated the molecular determinants of FQ resistance in Escherichia coli and Klebsiella pneumoniae isolates in Iran. METHODS: A total of 364 cli...
Topics
- Bacterial Proteins
- DNA Gyrase
- DNA Topoisomerase IV
- Drug Resistance, Bacterial
- Escherichia coli
- Escherichia coli Infections
- Humans
- Iran
- Klebsiella Infections
- Klebsiella pneumoniae