Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutralization escape, infectivity, and membrane fusion of JN.1-derived SARS-CoV-2 SLip, FLiRT, and KP.2 variants.

Cell reports - 27 Aug 2024

Li Pei, Faraone Julia N, Hsu Cheng Chih, Chamblee Michelle, Zheng Yi-Min, Carlin Claire, Bednash Joseph S, Horowitz Jeffrey C, Mallampalli Rama K, Saif Linda J, Oltz Eugene M, Jones Daniel, Li Jianrong, Gumina Richard J, Xu Kai, Liu Shan-Lu

Abstract excerpt

We investigate JN.1-derived subvariants SLip, FLiRT, and KP.2 for neutralization by antibodies in vaccinated individuals, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients, or class III monoclonal antibody S309. Compared to JN.1, SLip, KP.2, and especially FLiRT exhibit increased resistance to bivalent-vaccinated and BA.2.86/JN.1-wave convalescent human sera. XBB.1.5...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to Antibodies, Neutralizing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Viral

Share to COVID-19 Vaccines

Share to Membrane Fusion

Share to Neutralization Tests

Share to Spike Glycoprotein, Coronavirus

Share to Vero Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 39024099
DOI: 10.1016/j.celrep.2024.114520
PMCID: PMC11430188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutralization escape, infectivity, and membrane fusion of JN.1-derived SARS-CoV-2 SLip, FLiRT, and KP.2 variants.PMID 39024099Read ↗

Characteristics of JN.1-derived SARS-CoV-2 subvariants SLip, FLiRT, and KP.2 in neutralization escape, infectivity and membrane fusionSemantic proximity Read ↗

Recurrent SARS-CoV-2 spike mutations confer growth advantages to select JN.1 sublineages.Semantic proximity Read ↗

Immune Evasion, Cell-Cell Fusion, and Spike Stability of the SARS-CoV-2 XEC Variant: Role of Glycosylation Mutations at the N-terminal DomainSemantic proximity Read ↗

Recurrent SARS-CoV-2 spike mutations confer growth advantages to select JN.1 sublineagesSemantic proximity Read ↗

Structural basis for the evolution and antibody evasion of SARS-CoV-2 BA.2.86 and JN.1 subvariants.Semantic proximity Read ↗

Rapid spread of the SARS-CoV-2 JN.1 lineage is associated with increased neutralization evasionSemantic proximity Read ↗

Pemivibart is less active against recent SARS-CoV-2 JN.1 sublineagesSemantic proximity Read ↗

Distinct Patterns of SARS-CoV-2 BA.2.87.1 and JN.1 Variants in Immune Evasion, Antigenicity and Cell-Cell FusionSemantic proximity Read ↗

Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes.Semantic proximity Read ↗

Neutralization and spike stability of JN.1-derived LB.1, KP.2.3, KP.3, and KP.3.1.1 subvariants.Semantic proximity Read ↗

Monoclonal Antibodies from COVID-19 Convalescent Patients Target Cryptic Epitopes for Universal SARS-CoV-2 NeutralizationSemantic proximity Read ↗

Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster modelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.