Article
NGS mutational status on first diagnostic tissue, liquid biopsy and mastectomy in G2-G3 breast cancer.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2000
Ardeleanu Carmen Maria, Olinca Maria Victoria, Viişoreanu Cristian Gabriel, Mureşan Horaţiu Alin, Tecuceanu-Vulpe Adriana, Manole Georgiana, Gune Iulia Elena, Gălăţeanu Bianca, Ilie-Petrov Andreea Corina, Ultimescu Flavia
Abstract excerpt
Breast cancer is one of the more frequently diagnosed cancers leading to death in women, and, like other tumor types, it is heterogeneous in its immunophenotype. It harbors mutations that modify tumor aggressiveness, therapy responses, residual disease, drug resistance, and relapse rates in advanced stages. This study aims to assess the mutational status of G2 and G3 tumors using next-generation sequencing (NGS)...
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