Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Point mutation P174L of the penA gene endowing ceftazidime resistance to Burkholderia pseudomallei in China.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 Sept 2024

Tian Shen, Wu Xingyong, Liu Lin, Li Anyang, Li Xuemiao, Pei Hua, Wang Yanshuang, Dance David A B, Chen Hai, Xia Qianfeng

Abstract excerpt

In a clinical isolate of Burkholderia pseudomallei from Hainan, the association between the emergence of ceftazidime resistance and a novel PenA P174L allele was identified for the first time, providing an understanding of one mechanism by which ceftazidime resistance arises in B. pseudomallei.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Burkholderia pseudomallei

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ceftazidime

Share to Drug Resistance, Bacterial

Share to Melioidosis

Share to Microbial Sensitivity Tests

Share to Point Mutation

Source

Identifiers

PMID: 39018660
DOI: 10.1016/j.drup.2024.101121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Point mutation P174L of the penA gene endowing ceftazidime resistance to Burkholderia pseudomallei in China.PMID 39018660Read ↗

Characterization of ceftazidime resistance mechanisms in clinical isolates of Burkholderia pseudomallei from Australia.Semantic proximity Read ↗

Genomic Insights into Ceftazidime Resistance in <i>Burkholderia pseudomallei</i> : Discovery of A172T Mutation, and Palindromic GC-Rich Repeat Sequences Facilitating <i>penA</i> Duplication and AmplificationSemantic proximity Read ↗

Antibiotic Resistance Markers in Burkholderia pseudomallei Strain Bp1651 Identified by Genome Sequence AnalysisSemantic proximity Read ↗

Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in <i>Burkholderia pseudomallei</i>Semantic proximity Read ↗

Development of ceftazidime resistance in an acute Burkholderia pseudomallei infectionSemantic proximity Read ↗

Identification of amino acids conferring high-level resistance to expanded-spectrum cephalosporins in the penA gene from Neisseria gonorrhoeae strain H041.Semantic proximity Read ↗

Burkholderia pseudomallei class a beta-lactamase mutations that confer selective resistance against ceftazidime or clavulanic acid inhibition.Semantic proximity Read ↗

Isolation of polymyxin B-susceptible mutants of Burkholderia pseudomallei and molecular characterization of genetic loci involved in polymyxin B resistance.Semantic proximity Read ↗

Research on the establishment and application of protein fingerprint spectrum database of Burkholderia pseudomallei in Hainan Province ChinaSemantic proximity Read ↗

[Molecular typing of the Burkholderia pseudomallei strains with different resistance to antibiotics].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.