Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitotic catastrophe heterogeneity: implications for prognosis and immunotherapy in hepatocellular carcinoma

1 Jul 2024

Abstract excerpt

Background and aims: The mitotic catastrophe (MC) pathway plays an important role in hepatocellular carcinoma (HCC) progression and tumor microenvironment (TME) regulation. However, the mechanisms linking MC heterogeneity to immune evasion and treatment response remain unclear. Methods: Based on 94 previously published highly correlated genes for MC, HCC patients' data from the Cancer Genome Atlas (TCGA) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Ferroptosis and cancer prognosis
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39015573
DOI: 10.3389/fimmu.2024.1409448

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitotic catastrophe heterogeneity: implications for prognosis and immunotherapy in hepatocellular carcinomaPMID 39015573Read ↗

Deciphering mitotic catastrophe–associated transcriptomic patterns to predict prognosis and immunotherapy response in renal cell carcinomaSemantic proximity Read ↗

High ratio of resident to exhausted CD4+ T cells predicts favorable prognosis and potentially better immunotherapeutic efficacy in hepatocellular carcinomaSemantic proximity Read ↗

Spatial maps of hepatocellular carcinoma transcriptomes highlight an unexplored landscape of heterogeneity and a novel gene signature for survivalSemantic proximity Read ↗

Conduction and validation of a novel mitotic spindle assembly related signature in hepatocellular carcinoma: prognostic prediction, tumor immune microenvironment and drug susceptibilitySemantic proximity Read ↗

Pyroptosis drives tumor progression and immune evasion in Hepatocellular Carcinoma: a single-cell and spatial transcriptomic studySemantic proximity Read ↗

Spatial Analysis Uncovers Immune Resistance Mechanisms in Non-Beneficial Hepatocellular Carcinoma Treated with Y90 Radioembolization-NivolumabSemantic proximity Read ↗

Integrating machine learning models with multi-omics analysis to decipher the prognostic significance of mitotic catastrophe heterogeneity in bladder cancerSemantic proximity Read ↗

Centrosome amplification-related signature correlated with immune microenvironment and treatment response predicts prognosis and improves diagnosis of hepatocellular carcinoma by integrating machine learning and single-cell analysesSemantic proximity Read ↗

Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver CancerSemantic proximity Read ↗

Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer.Semantic proximity Read ↗

Multidimensional Analysis of PANoptosis-Related Molecule CASP8: Prognostic Significance, Immune Microenvironment Effect, and Therapeutic Implications in Hepatocellular CarcinomaSemantic proximity Read ↗

Spatial Maps of Hepatocellular Carcinoma Transcriptomes Highlight an Unexplored Landscape of Heterogeneity and a Novel Gene Signature for SurvivalSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.