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Article

Genetic and non-genetic factors in prediction of early pubertal development in Chinese girls.

Frontiers in endocrinology - 1 Jan 2024

Li Weiqin, Du Yuexin, Feng Lingyan, Song Panpan, Wang Leishen, Zhang Shuang, Li Wei, Zhu Dandan, Liu Huikun

Abstract excerpt

Objective: The objective of this study is to develop a combined predictive model for early pubertal development (EPD) in girls based on both non-genetic and genetic factors. Methods: The case-control study encompassed 147 girls diagnosed with EPD and 256 girls who exhibited normal pubertal development. The non-genetic risk score (NGRS) was calculated based on 6 independent biochemical predictors screened by...

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Identifiers

PMID: 39010901
DOI: 10.3389/fendo.2024.1413528
PMCID: PMC11246873

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