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Article

Genetic diversity accelerates canine distemper virus adaptation to ferrets.

Journal of virology - 20 Aug 2024

Siering Oliver, Langbein Mareike, Herrmann Maike, Wittwer Kevin, von Messling Veronika, Sawatsky Bevan, Pfaller Christian K

Abstract excerpt

RNA viruses adapt rapidly to new host environments by generating highly diverse genome sets, so-called "quasispecies." Minor genetic variants promote their rapid adaptation, allowing for the emergence of drug-resistance or immune-escape mutants. Understanding these adaptation processes is highly relevant to assessing the risk of cross-species transmission and the safety and efficacy of vaccines and antivirals. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39007615
DOI: 10.1128/jvi.00657-24
PMCID: PMC11334482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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