Article
Vitamin D affects the risk of disease activity in multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry - 16 Jan 2025
Giordano Antonino, Clarelli Ferdinando, Pignolet Béatrice, Mascia Elisabetta, Sorosina Melissa, Misra Kaalindi, Ferrè Laura, Bucciarelli Florence, Manouchehrinia Ali, Moiola Lucia, Martinelli Vittorio, Rocca Maria A, Liblau Roland, Filippi Massimo, Esposito Federica
Abstract excerpt
BACKGROUND: Vitamin D (VitD) affects the risk of multiple sclerosis (MS), but the impact on disease activity is controversial. We assessed whether VitD is associated with the No-Evidence of Disease Activity-3 (NEDA-3) status at 2 years from disease-modifying treatment (DMT) start, and whether this association is causal or the result of confounding factors. Furthermore, we explored if a genetic predisposition to...
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