Article
Genetic Clustering of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Patients of Colorectal Origin: KRAS and Not TP53 Cluster Alterations are Associated with Poor Outcomes.
Annals of surgical oncology - 1 Sept 2024
Yu Allen T, Hanna David N, Li Thomas M, Sarfaty Elad, Khajoueinejad Nazanin, Li Judy, Golas Benjamin, Hiotis Spiros, Labow Daniel, Sarpel Umut, Magge Deepa R, Cohen Noah A
Abstract excerpt
BACKGROUND: The prognostic impact of genetic mutations for patients who undergo cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) of colorectal origin (CRC) is not well defined. OBJECTIVE: We aimed to describe the genetic classifications in an unsupervised fashion, and the outcomes of this patient population. METHODS: A retrospective, bi-institutional study was performed on...
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