Article
Effect of RAS and BRAF mutations on peritoneal metastasis risk and cytoreductive surgery/hyperthermic intraperitoneal chemotherapy efficacy in colorectal cancer: A systematic review and meta-analysis.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Sept 2024
Gao Ziming, Qi Xiang, Wang Ruiying, Wen Zhitong, Qi Hao, Ju Mingguang, Liu Xiaoxu, Wang Junye, Zhou Heng, Zhu Zhi, Liu Xiaofang, Li Kai
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) patients with peritoneal metastasis (CRC-PM) have a worse prognosis than those with liver and lung metastases. Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is an effective locoregional treatment for CRC-PM. To date, the prognostic analysis of CRS/HIPEC mostly focuses on clinical and pathological characteristics; however, genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.