GraphSlimmer: Preserving Read Mappability with the Minimum Number of Variants.

Abstract excerpt

Modern genomic datasets, like those generated under the 1000 Genome Project, contain millions of variants belonging to known haplotypes. Although these datasets are more representative than a single reference sequence and can alleviate issues like reference bias, they are significantly more computationally burdensome to work with, often involving large-indexed genome graph data structures for tasks such as read...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Computational Biology