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Article

Cellular adaptation to cancer therapy along a resistance continuum.

Nature - 1 Jul 2024

França Gustavo S, Baron Maayan, King Benjamin R, Bossowski Jozef P, Bjornberg Alicia, Pour Maayan, Rao Anjali, Patel Ayushi S, Misirlioglu Selim, Barkley Dalia, Tang Kwan Ho, Dolgalev Igor, Liberman Deborah A, Avital Gal, Kuperwaser Felicia, Chiodin Marta, Levine Douglas A, Papagiannakopoulos Thales, Marusyk Andriy, Lionnet Timothée, Yanai Itai

Abstract excerpt

Advancements in precision oncology over the past decades have led to new therapeutic interventions, but the efficacy of such treatments is generally limited by an adaptive process that fosters drug resistance1. In addition to genetic mutations2, recent research has identified a role for non-genetic plasticity in transient drug tolerance3 and the acquisition of stable resistance4,5. However, the dynamics of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38987605
DOI: 10.1038/s41586-024-07690-9
PMCID: PMC11925205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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