Article
Whole exome sequencing reveals diverse genomic relatedness between paired concurrent endometrial and ovarian carcinomas.
European journal of cancer (Oxford, England : 1990) - 1 Sept 2024
Southworth Emily, Thomson John P, Croy Ian, Churchman Michael, Arends Mark J, Hollis Robert L, Gourley Charlie, Herrington C Simon
Abstract excerpt
INTRODUCTION: Concurrent non-serous endometrial and ovarian tumours are often managed clinically as two separate primary tumours, but almost all exhibit evidence of a genomic relationship. METHODOLOGY: This study investigates the extent of relatedness using whole exome sequencing, which was performed on paired non-serous endometrial and ovarian carcinomas from 27 patients with concurrent tumours in a cohort with...
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