Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Physiologic medium renders human iPSC-derived macrophages permissive for M. tuberculosis by rewiring organelle function and metabolism

10 Jul 2024

Abstract excerpt

ABSTRACT In vitro studies are crucial for our understanding of the human macrophage immune functions. However, traditional in vitro culture media poorly reflect the metabolic composition of blood, potentially affecting the outcomes of these studies. Here, we analyzed the impact of a physiological medium on human induced pluripotent stem cell (iPSC)-derived macrophages (iPSDM) function. Macrophages cultured in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Immune cells in cancer
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38984828
DOI: 10.1128/mbio.00353-24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Physiologic medium renders human iPSC-derived macrophages permissive for M. tuberculosis by rewiring organelle function and metabolismPMID 38984828Read ↗

A streamlined and comprehensive protocol for the generation and multi-omic analysis of human monocyte-derived macrophagesSemantic proximity Read ↗

Human Plasma-Like Medium Promotes Maturation of Human Pluripotent Stem Cell-Derived CardiomyocytesSemantic proximity Read ↗

Cultivation of Cells in a Physiological Plasmax Medium Increases Mitochondrial Respiratory Capacity and Reduces Replication Levels of RNA VirusesSemantic proximity Read ↗

TREM2 <sup>+</sup> macrophages accumulate in alveoli of human pulmonary tuberculosis providing a permissive niche for bacterial growthSemantic proximity Read ↗

Systems analysis reveals alternate metabolic states adopted by <i>Mycobacterium tuberculosis</i> across speciesSemantic proximity Read ↗

Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease.Semantic proximity Read ↗

A new tractable method for generating Human Alveolar Macrophage Like cells in vitro to study lung inflammatory processes and diseasesSemantic proximity Read ↗

Cell metabolism: Functional and phenotypic single cell approaches.Semantic proximity Read ↗

Nanomaterial-Based Repurposing of Macrophage Metabolism and Its ApplicationsSemantic proximity Read ↗

Effects of Metabolism on Macrophage Polarization Under Different Disease Backgrounds.Semantic proximity Read ↗

Cytokine-induced reprogramming of human macrophages toward Alzheimer's disease-relevant molecular and cellular phenotypes in vitro.Semantic proximity Read ↗

Optimized culture of primary human alveolar type II cell-derived 3D organoids from fibrotic lung tissue with phenotypic and metabolic profiling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.