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Role of Cytochrome P450 3A4 in Cancer Drug Resistance: Challenges and Opportunities

1 May 2024

Abstract excerpt

One of the biggest obstacles to the treatment of diseases, particularly serious conditions like cancer, is therapeutic resistance. The process of drug resistance is influenced by a number of important variables, including MDR genes, drug efflux, low-quality medications, inadequate dosage, etc. Drug resistance must be addressed, and new combinations based on the pharmacokinetics/pharmacodynamics (PK-PD)...

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PMID: 38984579
DOI: 10.2174/0113892002312369240703102215

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