Article
Risk for breast cancer and management of unaffected individuals with non-BRCA hereditary breast cancer.
The breast journal - 1 Aug 2020
Wood Marie E, McKinnon Wendy, Garber Judy
Abstract excerpt
About 5%-10% of breast cancer is hereditary with BRCA1 and BRCA2 being the most common genes associated with hereditary breast cancer (HBC). Several additional genes have recently been associated with HBC. These genes can be classified as highly or moderately penetrant genes with lifetime risk >30% or 17%-30%, respectively. Highly penetrant genes associated with HBC include TP53, PTEN, CDH1, STK11, and PALB2....
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