Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Advance on TERT gene in melanoma].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Jul 2024

Zheng Y X, Zhang X, Su J

Abstract excerpt

皮肤黑色素瘤恶性程度高，基因改变复杂。端粒酶逆转录酶（telomerase reverse transcriptase，TERT）是黑色素瘤中较常出现异常的基因。TERT基因在黑色素瘤中的异常主要包括TERT启动子突变和TERT扩增，前者较常见于非肢端皮肤黑色素瘤，后者较常见于肢端黑色素瘤。检测TERT基因异常对黑色素细胞肿瘤良恶性鉴别，黑色素瘤的预后判断均有重要价值。同时，对阐明黑色素瘤发生的分子机制，寻求新的靶向治疗手段也有一定提示意义。.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Telomerase
Share to Gene Amplification
Share to Melanoma
Share to Melanoma, Cutaneous Malignant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Prognosis

Share to Promoter Regions, Genetic

Share to Skin Neoplasms

Source

Identifiers

PMID: 38955717
DOI: 10.3760/cma.j.cn112151-20231106-00337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Advance on TERT gene in melanoma].PMID 38955717Read ↗

TERT Promoter Mutations and Telomerase in MelanomaSemantic proximity Read ↗

TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic ApoptosisSemantic proximity Read ↗

TERT promoter mutations in cancer development.Semantic proximity Read ↗

TERT—Regulation and Roles in Cancer FormationSemantic proximity Read ↗

[Melanoma and search for therapeutic targets].Semantic proximity Read ↗

TERT mutations in Malignant Melanoma-Survival Meta-AnalysisSemantic proximity Read ↗

<i>TERT</i> expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entitiesSemantic proximity Read ↗

TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities.Semantic proximity Read ↗

TERT promoter mutations associate with fast‐growing melanomaSemantic proximity Read ↗

Telomerase Activity in Melanoma: Impact on Cancer Cell Proliferation Kinetics, Tumor Progression, and Clinical Therapeutic Strategies—A Scoping ReviewSemantic proximity Read ↗

A promising preclinical model for TERT promoter mutation in glioblastoma.Semantic proximity Read ↗

Highly recurrent TERT promoter mutations in human melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.