Article
Application of a newly constructed NGS panel with 45 X-linked microhaplotypes demonstrates the unique value of X-MH for kinship testing and mixture analysis.
Forensic science international. Genetics - 1 Sept 2024
Ma Guanju, Liu Kailiang, Lu Chaolong, Du Qingqing, Zhang Mengjie, Wang Qian, Fu Guangping, Wang Junyan, Ma Chunling, Cong Bin, Li Shujin, Fu Lihong
Abstract excerpt
X-linked microhaplotypes (X-MHs) have the potential to be a valuable supplementary tool in complex kinship identification or the resolution of DNA mixtures, because they bring together the distinctive genetic pattern of X chromosomal markers and the benefits of microhaplotypes (MHs). In this study, we used the 1000 Genome database to screen and select 63 X-MHs; 18 MHs were filtered out though a batch sequencing...
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