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Clonal Hematopoiesis-Associated Gene Mutations Affect Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation in AML Patients.

Annals of transplantation - 2 Jul 2024

Wei Xiaoxuan, Huang Sai, Gu Zhenyang, Liu Jing, Li Meng, Jin Xiangshu, Bo Jian, Li Fei, Jing Yu, Gao Xiaoning, Dou Liping, Liu Daihong, Gao Chunji

Abstract excerpt

BACKGROUND The relationship between clonal hematopoiesis (CH)-associated gene mutations and allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been extensively studied since next-generation sequencing (NGS) technology became widely available. However, research has mainly focused on the relationship between donor CH mutations and transplant prognosis, and research into the relationship between CH...

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Identifiers

PMID: 38952007
DOI: 10.12659/AOT.943688
PMCID: PMC11299484

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