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Use of Whole Genome Sequencing for Mycobacterium tuberculosis Complex Antimicrobial Susceptibility Testing: From Sequence Data to Resistance Profiles.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Dreyer Viola, Sonnenkalb Lindsay, Diricks Margo, Utpatel Christian, Barilar Ivan, Mohr Vanessa, Niemann Stefan, Kohl Thomas A, Merker Matthias

Abstract excerpt

Whole genome sequencing of Mycobacterium tuberculosis complex (MTBC) isolates has been shown to provide accurate predictions for resistance and susceptibility for many first- and second-line anti-tuberculosis drugs. However, bioinformatic pipelines and mutation catalogs to predict antimicrobial resistances in MTBC isolates are often customized and detailed protocols are difficult to access. Here, we provide a...

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PMID: 38949712
DOI: 10.1007/978-1-0716-3981-8_18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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