Article
Common genetic variants associated with urinary phthalate levels in children: A genome-wide study.
Environment international - 1 Aug 2024
Bustamante Mariona, Balagué-Dobón Laura, Buko Zsanett, Sakhi Amrit Kaur, Casas Maribel, Maitre Lea, Andrusaityte Sandra, Grazuleviciene Regina, Gützkow Kristine B, Brantsæter Anne-Lise, Heude Barbara, Philippat Claire, Chatzi Leda, Vafeiadi Marina, Yang Tiffany C, Wright John, Hough Amy, Ruiz-Arenas Carlos, Nurtdinov Ramil N, Escaramís Geòrgia, González Juan R, Thomsen Cathrine, Vrijheid Martine
Abstract excerpt
INTRODUCTION: Phthalates, or dieters of phthalic acid, are a ubiquitous type of plasticizer used in a variety of common consumer and industrial products. They act as endocrine disruptors and are associated with increased risk for several diseases. Once in the body, phthalates are metabolized through partially known mechanisms, involving phase I and phase II enzymes. OBJECTIVE: In this study we aimed to identify...
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