Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of susceptibility to phthalate and DINCH exposure through CYP and UGT single nucleotide polymorphisms.

Environment international - 15 Jan 2022

Stajnko Anja, Runkel Agneta Annika, Kosjek Tina, Snoj Tratnik Janja, Mazej Darja, Falnoga Ingrid, Horvat Milena

Abstract excerpt

Single nucleotide polymorphisms (SNPs) of cytochrome P450 (CYPs) and UDP-glucuronosyltransferase (UGTs) genes have been proposed to influence phthalates and 1,2-cyclo-hexanedicarboxylic acid diisononyl ester (DINCH) biotransformation but have not been investigated on a populational level. We investigated the role of SNPs in CYP2C9, CYP2C19, CYP2D6, UGT2B15, and UGT1A7 genes in the biotransformation of phthalates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 Enzyme System
Share to Environmental Exposure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Environmental Pollutants

Share to Lactation

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 34920277
DOI: 10.1016/j.envint.2021.107046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of susceptibility to phthalate and DINCH exposure through CYP and UGT single nucleotide polymorphisms.PMID 34920277Read ↗

Common genetic variants associated with urinary phthalate levels in children: a genome-wide studySemantic proximity Read ↗

Common genetic variants associated with urinary phthalate levels in children: A genome-wide study.Semantic proximity Read ↗

Prenatal phthalate exposure and cord blood DNA methylationSemantic proximity Read ↗

Urinary Phthalate Metabolites in Pregnant Women: Occurrences, Predictors, and Association with Maternal HormonesSemantic proximity Read ↗

Association of maternal phthalates exposure and metabolic gene polymorphisms with congenital heart diseases: a multicenter case-control study.Semantic proximity Read ↗

Preconception urinary phthalate concentrations and sperm DNA methylation profiles among men undergoing IVF treatment: a cross-sectional studySemantic proximity Read ↗

Urinary concentration of endocrine-disrupting phthalates and breast cancer risk in Indian women: A case-control study with a focus on mutations in phthalate-responsive genes.Semantic proximity Read ↗

Modulation of urinary polycyclic aromatic hydrocarbon metabolites by enzyme polymorphisms in workers of the German Human Bitumen Study.Semantic proximity Read ↗

NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-n-butyl phthalateSemantic proximity Read ↗

Prenatal exposure to drinking-water chlorination by-products, cytochrome P450 gene polymorphisms and small-for-gestational-age neonates.Semantic proximity Read ↗

Oxidative Stress-Related Genetic Variants May Modify Associations of Phthalate Exposures with Asthma.Semantic proximity Read ↗

The correlation between UDP-glucuronosyltransferase polymorphisms and environmental endocrine disruptors levels in polycystic ovary syndrome patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.