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Article

Two-sample Mendelian randomization studies revealed a causal relationship between insulin use and osteoporosis: An observational study.

Medicine - 28 Jun 2024

Wang Zhan, Zhou Yu-Bo, Wang Long, Wang Lei, Wang Zhenbin, Chen Ping-Bo

Abstract excerpt

OBJECTIVE: To investigate causal associations between diabetes, insulin treatment and osteoporosis using LDSC analysis with a 2-way Mendelian randomization study. METHODS: LDSC analysis was used to estimate the likelihood-scale heritability of the genome-wide association study used with genetic correlation between the 2 genome-wide association study used. Then a 2-sample Mendelian randomization study was...

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Identifiers

PMID: 38941431
DOI: 10.1097/MD.0000000000038535
PMCID: PMC11466163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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