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Article

Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis.

Journal of translational medicine - 27 Jun 2024

Zhang Miaomiao, Zhang Jinghao, Hu Haisheng, Zhou Yuan, Lin ZhiWei, Jing Hui, Sun Baoqing

Abstract excerpt

BACKGROUND: Monocyte-derived alveolar macrophages (Mo_AMs) are increasingly recognised as potential pathogenic factors for idiopathic pulmonary fibrosis (IPF). While scRNAseq analysis has proven valuable in the transcriptome profiling of Mo_AMs, the integration analysis of multi-omics may provide additional dimensions of understanding of these cellular populations. METHODS: We performed multi-omics analysis on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38937806
DOI: 10.1186/s12967-024-05398-y
PMCID: PMC11209973

Genes

APOE
BACH2
CXCL12
CXCR4
FOSL2
JUNB
JUND
SMARCC1
SPIB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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