Article

ScRNA-seq Expression of <i>IFI27</i> and <i>APOC2</i> Identifies Four Alveolar Macrophage Superclusters in Healthy BALF

2022-01-30

Abstract excerpt

Alveolar macrophages (AMs) reside on the luminal surface of the airways and alveoli, ensuring proper gas exchange by ingesting cellular debris and pathogens, and regulating inflammatory responses. Therefore, understanding the heterogeneity and diverse roles played by AMs, interstitial macrophages (IMs), and recruited monocytes is critical for treating airway diseases. We performed single-cell RNA sequencing on 113...

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Literature Corpus work: 20432cd8-8d51-597d-9d4d-ada648019281
DOI: 10.1101/2022.01.30.478325

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