Article
Potential of pharmacogenetics in minimizing drug therapy problems in cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Sept 2024
Chhibber Anindit, Watanabe Alexandre Hikiji, Jacobs Hollyann, Kharat Aditi, Syeed Sakil M, Sherwin Catherine M, Chaiyakunapruk Nathorn, Biskupiak Joseph, Yellepeddi Venkata K, Brixner Diana, Young David C
Abstract excerpt
BACKGROUND: With advancements in CF drug development, people with cystic fibrosis (PwCF) now take a median of seven medications daily, increasing treatment complexity, risk of drug therapy problems (DTPs), and interference with treatment goals. Given that some of these DTPs can be prevented with preemptive pharmacogenetic testing, the overall goal of this study was to test the clinical utility of a multi-gene...
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