Article
Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping.
Clinical pharmacology and therapeutics - 1 Aug 2012
Schildcrout J S, Denny J C, Bowton E, Gregg W, Pulley J M, Basford M A, Cowan J D, Xu H, Ramirez A H, Crawford D C, Ritchie M D, Peterson J F, Masys D R, Wilke R A, Roden D M
Abstract excerpt
Routine integration of genotype data into drug decision making could improve patient safety, particularly if many relevant genetic variants can be assayed simultaneously before prescribing the target drug. The frequency of opportunities for pharmacogenetic prescribing and the potential adverse events (AEs) mitigated are unknown. We examined the frequency with which 56 medications with known outcomes influenced by...
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