Article
Contributions of the anaplerotic reaction enzymes pyruvate carboxylase and phosphoenolpyruvate carboxylase to l-lysine production in Corynebacterium glutamicum.
Journal of bioscience and bioengineering - 1 Sept 2024
Shinmori Akinobu, Guo Zhen, Maeda Tomoya, Fukiya Satoru, Wada Masaru, Yokota Atsushi
Abstract excerpt
Anaplerotic reactions catalyzed by pyruvate carboxylase (PC) and phosphoenolpyruvate carboxylase (PEPC) have important roles in the production of l-lysine to replenish oxaloacetic acid (OAA) in Corynebacterium glutamicum. However, the relative contributions of these enzymes to l-lysine production in C. glutamicum are not fully understood. In this study, using a parent strain (P) carrying a feedback...
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