Article
A newly identified gene Ahed plays essential roles in murine haematopoiesis.
Nature communications - 25 Jun 2024
Nakai Ritsuko, Yokota Takafumi, Tokunaga Masahiro, Takaishi Mikiro, Yokomizo Tomomasa, Sudo Takao, Shi Henyun, Yasumizu Yoshiaki, Okuzaki Daisuke, Kokubu Chikara, Tanaka Sachiyo, Takaoka Katsuyoshi, Yamanishi Ayako, Yoshida Junko, Watanabe Hitomi, Kondoh Gen, Horie Kyoji, Hosen Naoki, Sano Shigetoshi, Takeda Junji
Abstract excerpt
The development of haematopoiesis involves the coordinated action of numerous genes, some of which are implicated in haematological malignancies. However, the biological function of many genes remains elusive and unknown functional genes are likely to remain to be uncovered. Here, we report a previously uncharacterised gene in haematopoiesis, identified by screening mutant embryonic stem cells. The gene,...
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