Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of multidrug efflux pump (AcrAB-TolC) in Enterobacter cloacae isolates from clinical samples.

Scientific reports - 13 Jun 2026

Akbar Sajeela, Khan Sumera Afzal, Khan Muhammad Ajmal, Asim Noreen, Hamayun Muhammad

Abstract excerpt

In Gram-negative bacterial pathogens, multidrug efflux pump's role is being studied as one of the critical mechanisms to develop antibiotics resistance. The current study was designed to characterize the AcrAB-TolC efflux pump genes to determine its role in multidrug resistance of hospital-acquired Enterobacter cloacae. In this cross-sectional descriptive study, a total of 200 clinical samples were collected for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carrier Proteins

Share to Drug Resistance, Multiple, Bacterial

Share to Enterobacter cloacae

Share to Enterobacteriaceae Infections

Share to Membrane Transport Proteins

Share to Microbial Sensitivity Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 42288528
DOI: 10.1038/s41598-026-53813-9
PMCID: PMC13376788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of multidrug efflux pump (AcrAB-TolC) in Enterobacter cloacae isolates from clinical samples.PMID 42288528Read ↗

Update on Multidrug Resistance Efflux Pumps in Acinetobacter spp.Semantic proximity Read ↗

Clinical Status of Efflux Resistance Mechanisms in Gram-Negative BacteriaSemantic proximity Read ↗

Efflux pump systems as key contributors to multidrug resistance in Stenotrophomonas maltophilia: Physiological roles and gene regulationSemantic proximity Read ↗

Phenotypic Characterization of Multidrug-resistant Escherichia Coli with Special Reference to Extended-spectrum-beta-lactamases and Metallo-beta-lactamases in a Tertiary Care Center.Semantic proximity Read ↗

Efflux-Mediated Resistance in Enterobacteriaceae: Recent Advances and Ongoing Challenges to Inhibit Bacterial Efflux PumpsSemantic proximity Read ↗

Multidrug resistance in enteric and other Gram-negative bacteriaSemantic proximity Read ↗

Molecular mechanisms associated with quinolone resistance in Enterobacteriaceae: review and updateSemantic proximity Read ↗

Drug Efflux Pump Inhibitors: A Promising Approach to Counter Multidrug Resistance in Gram-Negative Pathogens by Targeting AcrB Protein from AcrAB-TolC Multidrug Efflux Pump from Escherichia coliSemantic proximity Read ↗

Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteriaSemantic proximity Read ↗

Mechanisms of antimicrobial resistance in Stenotrophomonas maltophilia: a review of current knowledge.Semantic proximity Read ↗

Multidrug efflux pumps and their role in antibiotic and antiseptic resistance: a pharmacodynamic perspectiveSemantic proximity Read ↗

Function and Inhibitory Mechanisms of Multidrug Efflux PumpsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.