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Extending the sequences of HLA class I alleles without full-length genomic coverage using single molecule real-time DNA sequencing.

HLA - 1 Mar 2020

Hassall Kylara B, Latham Katy, Robinson James, Gymer Arthur, Goodall Rebecca, Merlo Dario, Marsh Steven G E, Mayor Neema P

Abstract excerpt

The assignment of an HLA allele name to a sequence requires a comparison between the generated target sequence and a reference sequence on the IPD-IMGT/HLA database. Absence of a full-length reference sequence can result in the inability of HLA typing software to accurately compare and assign the sequence. We sequenced the most frequently seen HLA class I alleles on the Anthony Nolan register present in the...

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PMID: 31916686
DOI: 10.1111/tan.13800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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