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Article

Sleep patterns and the risk of psoriatic disease: genetic predisposition and metabonomics.

The British journal of dermatology - 18 Feb 2026

Guo Ziyu, Luo Zehao, Zhang Shiyu, Yu Yao, Wu Zihua, Chen Yangqian, Sun Yuming, Zeng Furong, Shi Lin, Zhou Guowei, Lu Lixia, Deng Guangtong

Abstract excerpt

BACKGROUND: The longitudinal impact of comprehensive sleep patterns on incident psoriatic disease (PsD) and the potential mediating effects are unclear. OBJECTIVES: To investigate the associations of sleep patterns with PsD risk, alongside the role of genetic predisposition and the potential mediating effects of serum metabolites. METHODS: This prospective cohort study included 399 912 participants without PsD...

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PMID: 41240371
DOI: 10.1093/bjd/ljaf463

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