Article
A genome-wide cross-trait analysis identifies shared loci and causal relationships of obesity and lipidemic traits with psoriasis.
Frontiers in immunology - 1 Jan 2024
Wu Yuan, Huang Mengfen, Chen Xueru, Wu Jingjing, Li Li, Wei Jianan, Lu Chuanjian, Han Ling, Lu Yue
Abstract excerpt
Background: Obesity and dyslipidemia, major global health concerns, have been linked to psoriasis, but previous studies faced methodological limitations and their shared genetic basis remains unclear. This study examines various obesity-related and lipidemic traits as potential contributors to psoriasis development, aiming to clarify their genetic associations and potential causal links. Methods: Summary...
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