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Article

CARD9 in the pathogenesis of axial spondyloarthritis.

Best practice & research. Clinical rheumatology - 1 May 2024

Seufert A L, Struthers H, Caplan L, Napier R J

Abstract excerpt

Axial spondyloarthritis (axSpA) has been long classified as an autoimmune disease caused by a breakdown in the ability of the immune system to delineate self from foreign, resulting in self-reactive T cells. The strong genetic association of HLA-B27 supports this role for T cells. More recently, genetic and clinical studies indicate a prominent role of the environment in triggering axSpA, including an important...

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Identifiers

PMID: 38897880
DOI: 10.1016/j.berh.2024.101964
PMCID: PMC11534080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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