Article
Genetics and the axial spondyloarthritis spectrum.
Rheumatology (Oxford, England) - 1 Oct 2020
Brown Matthew A, Xu Huji, Li Zhixiu
Abstract excerpt
The axial SpAs (axSpAs) are clearly clinically a heterogeneous set of diseases with markedly varying extra-articular features. These diseases are all highly heritable and have overlapping but differing genetic origins. Shared features include association with HLA class I alleles and genes of the IL-23 pathway, among other things. Significant differences do exist however, both in the genetic loci involved and at...
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