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Article

Acute Erythroid Leukemia: From Molecular Biology to Clinical Outcomes.

International journal of molecular sciences - 6 Jun 2024

Fernandes Priyanka, Waldron Natalie, Chatzilygeroudi Theodora, Naji Nour Sabiha, Karantanos Theodoros

Abstract excerpt

Acute Erythroid Leukemia (AEL) is a rare and aggressive subtype of Acute Myeloid Leukemia (AML). In 2022, the World Health Organization (WHO) defined AEL as a biopsy with ≥30% proerythroblasts and erythroid precursors that account for ≥80% of cellularity. The International Consensus Classification refers to this neoplasm as "AML with mutated TP53". Classification entails ≥20% blasts in blood or bone marrow biopsy...

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Topics

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Share to GATA1 gene
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Share to Leukemia, Erythroblastic, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38892446
DOI: 10.3390/ijms25116256
PMCID: PMC11172574

Genes

TP53
CDX4
GATA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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