Article
To bi or not to bi: Acute erythroid leukemias and hematopoietic lineage choice.
Experimental hematology - 1 May 2021
Di Genua Cristina, Nerlov Claus
Abstract excerpt
Acute erythroid leukemia (AEL) is an acute leukemia characterized by erythroid lineage transformation. The World Health Organization (WHO) 2008 classification recognized two subtypes of AEL: bilineage erythroleukemia (erythroid/myeloid leukemia) and pure erythroid leukemia. The erythroleukemia subtype was removed in the updated 2016 WHO classification, with about half of cases reclassified as myelodysplastic...
Topics
- Animals
- Epigenesis, Genetic
- Erythroid Cells
- Gene Expression Regulation, Leukemic
- Humans
- Leukemia, Erythroblastic, Acute
- Leukemia, Myeloid, Acute
- Mutation
- Myelodysplastic Syndromes
