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Chemotherapeutics for Acute Erythroid Leukemia: Research, Present and Future.

Current molecular medicine - 1 Jan 2021

Liao Zexi, Li Jiaxin, Wu Jingjing, Liu Jing, Sun Shuming

Abstract excerpt

Acute erythroid leukemia (AEL) is a subtype of acute myeloid leukemia (AML) with features such as accumulation of maturation-arrested erythroblasts. Compared with AML, the progression of AEL is faster and the prognosis to available therapy is worse. However, its categorization is still being updated and the pathophysiology of AEL is still under research, making diagnosis and chemotherapy challenging for...

Topics

Cell Differentiation
Humans
Leukemia, Erythroblastic, Acute
Mutation
Neoplasm Proteins
Transcription Factors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33475071
DOI: 10.2174/1566524021666210121142316

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