Revisiting gene mutations and prognosis of ex-M6a-acute erythroid leukemia with regard to the new WHO classification

Abstract excerpt

Due to the lack of specific clinical and biological features, M6a-acute erythroid leukemia (M6a-AEL), defined as an erythroid/myeloid type of acute leukemia, is no longer a distinct entity in the last classification of myeloid neoplasms by the World Health Organization (WHO). 1 The diagnosis of M6a-AEL was previously made if a proliferation of erythroid precursors ⩾ 50% with a myeloblast count ⩾ 20% when counted...

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