Article
Resolution of RHCE Haplotype Ambiguities in Transfusion Settings.
International journal of molecular sciences - 28 May 2024
Izard Caroline, Laget Laurine, Beley Sophie, Bichel Nelly, De Boisgrollier Lugdivine, Picard Christophe, Chiaroni Jacques, Di Cristofaro Julie
Abstract excerpt
Red blood cell (RBC) transfusion, limited by patient alloimmunization, demands accurate blood group typing. The Rh system requires specific attention due to the limitations of serological phenotyping methods. Although these have been compensated for by molecular biology solutions, some RhCE ambiguities remain unresolved. The RHCE mRNA length is compatible with full-length analysis and haplotype discrimination,...
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