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Article

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy.

Molecular cancer - 9 Jan 2024

Chehelgerdi Mohammad, Chehelgerdi Matin, Khorramian-Ghahfarokhi Milad, Shafieizadeh Marjan, Mahmoudi Esmaeil, Eskandari Fatemeh, Rashidi Mohsen, Arshi Asghar, Mokhtari-Farsani Abbas

Abstract excerpt

The CRISPR system is a revolutionary genome editing tool that has the potential to revolutionize the field of cancer research and therapy. The ability to precisely target and edit specific genetic mutations that drive the growth and spread of tumors has opened up new possibilities for the development of more effective and personalized cancer treatments. In this review, we will discuss the different CRISPR-based...

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Identifiers

PMID: 38195537
DOI: 10.1186/s12943-023-01925-5
PMCID: PMC10775503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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