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Article

BACH2: The Future of Induced T-Regulatory Cell Therapies

22 May 2024

Abstract excerpt

BACH2 (BTB Domain and CNC Homolog 2) is a transcription factor that serves as a central regulator of immune cell differentiation and function, particularly in T and B lymphocytes. A picture is emerging that BACH2 may function as a master regulator of cell fate that is exquisitely sensitive to cell activation status. In particular, BACH2 plays a key role in stabilizing the phenotype and suppressive function of...

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PMID: 38891024
DOI: 10.3390/cells13110891

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