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Article

Deciphering the molecular landscape: evolutionary progression from gynecomastia to aggressive male breast cancer.

Cellular oncology (Dordrecht, Netherlands) - 1 Oct 2024

Yang Chuang, Wang Zhonglin, Qian Lijun, Fu Jingyue, Sun Handong

Abstract excerpt

BACKGROUND: Gynecomastia denotes the benign proliferation of glandular breast tissue and stands as a recognized risk factor for male breast cancer. Nonetheless, the underlying carcinogenic mechanisms orchestrating the progression from gynecomastia to cancer remain poorly understood. METHODS: This study employed single-cell RNA sequencing (scRNA-seq) to meticulously dissect the cellular landscape of gynecomastia...

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Share to Breast Neoplasms, Male
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA Copy Number Variations

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 38888848
DOI: 10.1007/s13402-024-00964-4
PMCID: PMC12974076

Genes

FGF7
FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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