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Associations with other cancer-related biomarkers might contribute to poor outcomes in RAS-altered, younger patients with colorectal cancer.

The oncologist - 6 Sept 2024

Kundranda Madappa N, Kemkes Ariane C, Evans Mark C, Flannery Cynthia A, Hall David W, Hoag Jess R, Therala Nishitha, Thakkar Snehal G, De La O Jean-Paul

Abstract excerpt

Colorectal cancer (CRC) is a common cancer in younger adults. In patients undergoing liver resection with RAS-altered CRCs, there is evidence suggesting younger patients have worse outcomes than older patients. To explain this pattern, differences in associations between RAS status and other cancer-related biomarkers in tumors from younger versus older patients with CRC were evaluated in a cohort of 925 patients...

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Share to Adenomatous Polyposis Coli Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

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Source

Open in PubMed Open full text

Identifiers

PMID: 38886182
DOI: 10.1093/oncolo/oyae153
PMCID: PMC11379647

Genes

APC
RNF43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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