Article
A critical review of RAF inhibitors in BRAF-mutated glioma treatment.
Pharmacogenomics - 1 Jan 2024
Khoury John-Victor El, Wehbe Sophie, Attieh Fouad, Boutros Marc, Kesrouani Carole, Kourie Hampig Raphaël
Abstract excerpt
BRAF gliomas have garnered significant attention in research due to the lack of effective treatments and their notable incidence, constituting 3% of all gliomas. This underlines the importance of investigating this area and the impact that targeted therapies could hold. This review discusses the development of targeted therapies for these tumors, examining the effectiveness of first-generation BRAF inhibitors...
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