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Transamniotic Stem Cell Therapy Modulates Uterine Natural Killer Cell Activity in the Hypoxia Model of Intrauterine Growth Restriction

14 Jun 2024

Abstract excerpt

Intrauterine growth restriction (IUGR) pathophysiology is driven by abnormal uterine natural killer cell (uNK) activity leading to placental dysfunction. Transamniotic stem cell therapy (TRASCET) with mesenchymal stem cells (MSCs) can improve experimental IUGR by mechanisms not fully understood. We sought to examine TRASCET’s effects in downstream products of uNKs in a model of IUGR: 15 Sprague–Dawley dams were...

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PMID: 38874223
DOI: 10.1089/scd.2023.0282

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